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KMID : 0371319930440050720
Journal of the Korean Surgical Society
1993 Volume.44 No. 5 p.720 ~ p.727
Usefulness of Duplex Doppler Ultrasonography in Renal Allograft Patient for the Evaluation of Renal Dysfunction
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Abstract
The differential diagnosis of various causes of renal allograft dysfunction has become increasingly difficult in the cyclosporine era even with biopsy as clinical signs and symptoms of rejection become more subtle. To investigate the efficacy of
duplex
Doppler Ultrasonography, duplex Doppler ultrasonography in 1661 renal transplant recipients from December 1989 to April 1991.
The findings of Doppler ultrasonography were correlated with 99mTc DTPA renography and clinical features retrospectively. Doppler signals were obtained from the main renal, segmental and interlobar arteries in each kidney. The signals were
quantified
using a resistive index(RI). RI values taken from all three arterial sites of each patients were averaged.
@ES The results were as follows:
@EN 1) The ratio of male to female was 109: 52, aged from 14 to 57 years with a mean age of 39 years.
2) Normal functioning graft were 112 patients with 187 studies. The mean value of RI was 0.58¡¾0.12. The acute rejection group was 31 patients with 70 studies and the mean value of RI was 0.78¡¾0.14 The chronic rejection group was 13 patients
with
16
studies and the mean value of RI was 0.69¡¾0.04. The infection group was 4 patients with 6 studies and the mean value of RI was 0.70¡¾0.05.
3) There was one case of acute tubular necrosis and its mean value of RI of two studies was 0.78¡¾0.05.
4) The acute rejection group and chronic rejection group revealed higher Rivalue than normal functioning group with statistical significance (normal functioning group vs acute rejection group; p<0.01/normal functioning group vs chronic rejection
group;
p<0.05 by ANOVA test). No statistical significance was found among acute rejection, chronic rejection and infection group.
We conclude that the color duplex Doppler ultrasonography is a simple, noninvasive diagnostic method to detect the dysfunction of grafted kidneys and to monitor the therapeutic response. But it has little value in differentiating the causes of
graft
dysfunction.
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